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MRT68921 HCl

CAS No. 2070014-87-6

MRT68921 HCl( —— )

Catalog No. M20090 CAS No. 2070014-87-6

MRT68921 hydrochloride is a potent inhibitor of both ULK1 and ULK2 (IC50s: 2.9 and 1.1 nM respectively).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    MRT68921 HCl
  • Note
    Research use only, not for human use.
  • Brief Description
    MRT68921 hydrochloride is a potent inhibitor of both ULK1 and ULK2 (IC50s: 2.9 and 1.1 nM respectively).
  • Description
    MRT68921 hydrochloride is a potent inhibitor of both ULK1 and ULK2 (IC50s: 2.9 and 1.1 nM respectively).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Autophagy
  • Target
    Autophagy
  • Recptor
    ULK1| ULK2
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2070014-87-6
  • Formula Weight
    471.04
  • Molecular Formula
    C25H34N6O·HCl
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 10 mg/mL;Water: 10 mg/mL
  • SMILES
    Cl.CN1CCc2cc(Nc3ncc(C4CC4)c(NCCCNC(=O)C4CCC4)n3)ccc2C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Petherick KJ et al. Pharmacological inhibition of ULK1 kinase blocks mammalian target of rapamycin (mTOR)-dependent autophagy. J Biol Chem. 2015 May 1;290(18):11376-83.
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